Regulation of lung endoderm progenitor cell behavior by miR302/367
نویسندگان
چکیده
منابع مشابه
In Vivo Regulation of the Zebrafish Endoderm Progenitor Niche by T-Box Transcription Factors
T-box transcription factors T/Brachyury homolog A (Ta) and Tbx16 are essential for correct mesoderm development in zebrafish. The downstream transcriptional networks guiding their functional activities are poorly understood. Additionally, important contributions elsewhere are likely masked due to redundancy. Here, we exploit functional genomic strategies to identify Ta and Tbx16 targets in earl...
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CD4(+)CD25(+)FoxP3(+) regulatory T cells (Tregs) possess the capacity to modulate both adaptive and innate immune responses. We hypothesized that Tregs could regulate hematopoiesis based on cytokine effector molecules they can produce. The studies here demonstrate that Tregs can affect the differentiation of myeloid progenitor cells. In vitro findings demonstrated the ability of Tregs to inhibi...
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The signaling pathway for Nodal, a ligand of the TGFβ superfamily, plays a central role in regulating the differentiation and/or maintenance of stem cell types that can be derived from the peri-implantation mouse embryo. Extra-embryonic endoderm stem (XEN) cells resemble the primitive endoderm of the blastocyst, which normally gives rise to the parietal and the visceral endoderm in vivo, but XE...
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The purification, renewal and differentiation of native cardiac progenitors would form a mechanistic underpinning for unraveling steps for cardiac cell lineage formation, and their links to forms of congenital and adult cardiac diseases. Previously, we have reported the identification of isl1+ cardiac progenitors in postnatal rat, mouse and human myocardium (1). The discovery of native cardiobl...
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ژورنال
عنوان ژورنال: Development
سال: 2011
ISSN: 1477-9129,0950-1991
DOI: 10.1242/dev.061762